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    • A rapid, sensitive, and specific assay to measure TF activity based on chromogenic determination of thrombin generation 

      Østerud, Bjarne; Latysheva, Nadezhda; Schoergenhofer, Christian; Jilma, Bernd; Hansen, John-Bjarne; Snir, Omri (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      Background - Most tissue factor (TF) activity assays are based on measurement of factor X (FX) activation by TF in the presence of factor VII (FVII)/FVIIa. This requires long incubation, which may result in TF-independent activity of FX and inaccurate measurement of TF activity.<p> <p>Aim - To develop a sensitive and specific TF activity assay, which does not register a non-specific TF activity, ...